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연구분야선천성 뇌발달질환 기전 규명 및 3D 질병모델링

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  • A Novel IRAK4/PIM1 Inhibitor Ameliorates Rheumatoid Arthritis and Lymphoid Malignancy by Blocking the TLR/MYD88-Mediated NF-kB Pathway
    Yoon SB*, Hong H*, Lim HJ, Choi J, Choi Y, Seo S, Lee H, Chae C, Park WK, Kim H, Jeong D, De TQ, Myung CS, Cho H
    Acta Pharmaceutica Sinica B, 2023
  • MeCP2 dysfunction prevents proper BMP signaling and neural progenitor expansion in brain organoid
    Hong H, Yoon SB, Park JE, Lee JI, Kim HY, Nam HJ, Cho H
    Annals of Clinical and Translational Neurology, 2023
  • Discovery of GSK3β Inhibitors through In Silico Prediction-and-Experiment Cycling Strategy, and Biological Evaluation
    Lee Y, Yoon SB, Hong H, Kim HY, Jung D, Moon BS, Park WK, Lee S, Kwon H, Park J, Cho H
    Molecules, 2022. 06.
  • MK5 Regulates YAP Stability and Is a Molecular Target in YAP-Driven Cancers
    Seo J, Kim MH, Hong H, Cho H, Park S, Kim SK, Kim J
    Cancer Research, 2019. 12.
  • Extraciliary roles of the ciliopathy protein JBTS17 in mitosis and neurogenesis
    Hong H*, Joo K*, Park S, Seo J, Kim M, Shin E, Cheong H, Lee J, & Kim J
    Annals of Neurology, 2019
  • Export of membrane proteins from the Golgi complex to the primary cilium requires the kinesin motor, KIFC1
    Lee S, Joo K, Jung E, Hong H, Seo J, & Kim J
    FASEB Journal, 2018
  • MCRS1 associates with cytoplasmic dynein and mediates pericentrosomal material recruitment
    Lee S, Lee M, Choi T, Hong H, Seo J, Kim C, & Kim J
    Scientific Reports, 2016
  • Actin Remodeling Confers BRAF Inhibitor Resistance to Melanoma Cells through YAP/TAZ Activation
    Kim M, Kim J, Hong H, Lee S, Lee J, Jung E, & Kim J
    EMBO Journal, 2016
  • Actin remodeling factors control ciliogenesis by regulating YAP/TAZ activity and vesicle trafficking
    Kim J, Jo H, Hong H, Kim M, Kim J, Lee J, Heo W, & Kim J
    Nature Communications, 2015
  • Myosin heavy chain 10 (MYH10) is required for centriole migration during the biogenesis of primary cilia
    Hong H, Kim J, & Kim J
    Biochemical and biophysical research communications, 2015