-
Deubiquitinase YOD1 Inhibition Suppresses DEX- and Denervation-Induced Muscle Atrophy Through MAFbx Destabilization
Jongbeom Chae#, Seon Min Woo#, Seung Un Seo, Simmyung Yook, Hyo Je Cho, Jung Yeol Lee, Kyoung Jin Min, Junhyeon Park, Dongryeol Ryu, Taeg Kyu Kwon*
Journal of cachexia, sarcopenia and muscle., 2026. 6. 1.
-
Enhanced anticancer efficacy of TRAIL-conjugated and odanacatib-loaded PLGA nanoparticles in TRAIL resistant cancer
Thoa Thi Kim Nguyen#, Seon Min Woo#, Seung Un Seo, Asmita Banstola, Haesoo Kim, Ramesh Duwa, An Thi Thanh Vu, In-Sun Hong, Taeg Kyu Kwon*, Simmyung Yook*
Biomaterials, 2026. 1. 1.
-
Non-canonical deubiquitination of OTUB1 induces IFNγ-mediated cell cycle arrest via regulation of p27 stability
Seul Gi Lee, Seon Min Woo, Seung Un Seo, Hyun Shik Lee, Sang Hyun Kim, Young-Chae Chang, Hyo Je Cho, Simmyung Yook, Ju-Ock Nam, Taeg Kyu Kwon*
Oncogene, 2024. 6. 1.
-
Cathepsin D promotes polarization of tumor-associated macrophages and metastasis through TGFBI-CCL20 signaling
Seul Gi Lee#, Seon Min Woo#, Seung Un Seo, Chan-Hyeong Lee, Moon-Chang Baek, Se Hwan Jang, Zee Yong Park, Simmyung Yook, Ju-Ock Nam, Taeg Kyu Kwon*
Experimental & molecular medicine, 2024. 2. 1.
-
Cathepsin K inhibition induces Raptor destabilization and mitochondrial dysfunction via Syk/SHP2/Src/OTUB1 axis-mediated signaling
Seung Un Seo#, Seon Min Woo#, Taeg Kyu Kwon*
Cell death & disease, 2023. 6. 17.
-
TGFBI remodels adipose metabolism by regulating the Notch-1 signaling pathway
Seul Gi Lee, Jongbeom Chae, Seon Min Woo, Seung Un Seo, Ha-Jeong Kim, Sang-Yeob Kim, David D Schlaepfer, In-San Kim, Hee-Sae Park, Taeg Kyu Kwon*, Ju-Ock Nam*
Experimental & molecular medicine, 2023. 3. 1.
-
Phosphorylation of OTUB1 at Tyr 26 stabilizes the mTORC1 component, Raptor
Seung Un Seo#, Seon Min Woo#, Min Wook Kim, Eun-Woo Lee*, Kyoung-Jin Min*, Taeg Kyu Kwon*
Cell death & differentiation, 2023. 1. 1.
-
Inhibition of USP1 enhances anticancer drugs-induced cancer cell death through downregulation of survivin and miR-216a-5p-mediated upregulation of DR5
Seon Min Woo#, Seok Kim#, Seung Un Seo, Shin Kim Jong-Wook Park, Gyeonghwa Kim, Yu-Ra Choi, Keun Hur, Taeg Kyu Kwon*
Cell death & disease, 2022. 9. 24.
-
BAP1 phosphorylation-mediated Sp1 stabilization plays a critical role in cathepsin K inhibition-induced C-terminal p53-dependent Bax upregulation
Seung Un Seo#, Seon Min Woo#, Seul Gi Lee, Min Yeong Kim, Hyun Shik Lee, Yung Hyun Choi, Sang Hyun Kim, Young-Chae Chang, Kyoung-Jin Min, Taeg Kyu Kwon*
Redox biology, 2022. 7. 1.
-
Itch and autophagy-mediated NF-κB activation contributes to inhibition of cathepsin D-induced sensitizing effect on anticancer drugs
Seung Un Seo#, Seon Min Woo#, Kyoung-Jin Min, Taeg Kyu Kwon
Cell death & disease, 2022. 6. 17.
-
Cathepsin D as a potential therapeutic target to enhance anticancer drug-induced apoptosis via RNF183-mediated destabilization of Bcl-xL in cancer cells
Seung Un Seo#, Seon Min Woo#, Seung-Soon Im, Younghoon Jang, Eugene Han, Sang Hyun Kim, Hongchan Lee, Hyun-Shik Lee, Ju-Ock Nam, Edward Gabrielson, Kyoung-Jin Min, Taeg Kyu Kwon*
Cell death & disease, 2022. 2. 4.
-
Inhibition of cathepsin K sensitizes oxaliplatin-induced apoptotic cell death by Bax upregulation through OTUB1-mediated p53 stabilization in vitro and in vivo
Seung Un Seo#, Seon Min Woo#, Shin Kim, Jong-Wook Park, Hyun-Shik Lee, Young-Seuk Bae, Sang Hyun Kim, Seung-Soon Im, Ji Hae Seo, Kyoung-Jin Min, Taeg Kyu Kwon*
Oncogene, 2022. 1. 1.
-
Melatonin induces apoptotic cell death through Bim stabilization by Sp1-mediated OTUD1 upregulation
Seon Min Woo#, Seung Un Seo#, Kyoung-Jin Min, Taeg Kyu Kwon*
Journal of pineal research, 2022. 1. 1.
-
Cathepsin K inhibition-induced mitochondrial ROS enhances sensitivity of cancer cells to anti-cancer drugs through USP27x-mediated Bim protein stabilization
Seung Un Seo, Seon Min Woo, Min Wook Kim, Hyun-Shik Lee, Sang Hyun Kim, Sun Chul Kang, Eun-Woo Lee, Kyoung-Jin Min, Taeg Kyu Kwon*
Redox biology, 2020. 2. 1.
