동산의료원 연구처

연구클리닉 연구처

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연구분야분자생물학을 기반으로 한 질환 발병기전 연구, 바이오마커 및 약물 타겟 발굴 연구

상담일시매주 수, 금 오전 9-12시

상담장소동산의생명연구센터 2층 회의실(M229) 또는 화상회의

논문 더보기
  • Disrupted astrocyte-neuron glutamine-glutamate cycling in the medial prefrontal cortex contributes to depression-like behaviors
    Jae Soon Kang, Ji Hyeong Baek, Hyeongchan Park, Naveed Ur Rehman, Hye Jin Chung, Dong Kun Lee, Sekyung Oh, Hyun Joon Kim
    International Journal of Biological Sciences, 2026.01
  • Tyrosine-containing small peptides from soy protein isolate act as an antidepressant against chronic immobilization stress–induced depressive male mice through glutamine synthetase activation
    Jae Soon Kang, Hyeongchan Park, Ji Hyeong Baek, Hyeju Kang, Rankyung Kim, Wonjune Jeong, Eunbin Hong, Soomin Han, Naveed Ur Rehman, Hye Jin Chung, Yeung Joon Choi, Dae Young Yoo, Sang Won Park, Hyun Joon Kim
    Food Bioscience, 2025.11
  • Activation of glutamine synthetase (GS) as a new strategy for the treatment of major depressive disorder and other GS- related diseases
    Jae Soon Kang, Hwajin Kim, Ji Hyeong Baek, Miyoung Song, Hyeongchan Park, Wonjune Jeong, Hye Jin Chung, Dae Young Yoo, Dong Kun Lee, Sang Won Park and Hyun Joon Kim
    Acta Pharmacologica Sinica, 2025.01
  • The Role of Glutamine Homeostasis in Emotional and Cognitive Functions
    Ji Hyeong Baek, Hyeongchan Park, Hyeju Kang, Rankyung Kim, Jae Soon Kang, Hyun Joon Kim
    International Journal of Molecular Science, 2024.01
  • Glutamine Supplementation Preserves Glutamatergic Neuronal Activity in the Infralimbic Cortex, Which Delays the Onset of Mild Cognitive Impairment in 3×Tg-AD Female Mice
    Ji Hyeong Baek, Jae Soon Kang, Miyoung Song, Dong Kun Lee, and Hyun Joon Kim
    Nutrients, 2023.06
  • Long-term exposure changes the environmentally relevant bis(2-ethylhexyl) phthalate to be a neuro-hazardous substance disrupting neural homeostasis in emotional and cognitive functions
    Jae Soon Kang, Ji Hyeong Baek, Mi yeong Song, Naveed Ur Rehman, Hye Jin Chung, Dong Kun Lee, Dae Young Yoo, Hyun Joon Kim
    Environmental Pollution, 2023.3
  • Long-term hyperglycemia causes depressive behaviors in mice with hypoactive glutamatergic activity in the medial prefrontal cortex, which Is not reversed by insulin treatment
    Ji Hyeong Baek, Hyeonwi Son, Jae Soon Kang, Dae Young Yoo, Hye Jin Chung, Dong Kun Lee, Hyun Joon Kim
    Cells, 2022.12
  • Isoflavone-enriched soybean leaves (Glycine max) alleviate cognitive impairment induced by ovariectomy and modulate PI3K/Akt signaling in the hippocampus of C57BL6 mice
    Dae Young Yoo, Soonwoong Jung, Jae Soon Kang, Ji Hyeong Baek, Ki Hun Park, Dong Hoon Lee, Sang Soo Kang, Hyun Joon Kim
    Nutrients, 2022.11
  • Combined water extracts from oxidation-treated leaves and branches of Hovenia dulcis has anti-hangover and liver protective effects in binge alcohol intake
    Jihyun Je, Miyoung Song, Ji Hyeong Baek, Jae Soon Kang, Hye Jin Chung, Kwonsu Lee, Sang Won Park, Hyun Joon Kim
    Nutrients, 2021.12
  • Acutely increased β-hydroxybutyrate plays a role in the prefrontal cortex to escape stressful conditions during the acute stress response
    Hyeonwi Son, Ji Hyeong Baek, Jae Soon Kang, Soonwoong Jung, Hye Jin Chung, Hyun Joon Kim
    Biochemical and Biophysical Research Communications, 2021.03
  • Ingestion of Bis(2-ethylhexyl) phthalate (DEHP) during adolescence causes depressive-like behaviors through hypoactive glutamatergic signaling in the medial prefrontal cortex
    Jae Soon Kang, Ji Hyeong Baek, Soonwoong Jung, Hye Jin Chung, Dong Kun Lee, Hyun Joon Kim
    Environ. Pollut., 2021
  • Glutamine supplementation prevents chronic stress-induced mild cognitive impairment
    Ji Hyeong Baek, Soonwoong Jung, Hyeonwi Son, Jae Soon Kang, and Hyun Joon Kim
    Nutrients, 2020.04
  • Glutamine supplementation ameliorates chronic stress-induced reductions in glutamate and glutamine transporters in the mouse prefrontal cortex
    Ji Hyeong Baek, Arul Vignesh, Hyeonwi Son, Dong Hoon Lee, Gu Seob Roh, Sang Soo Kang, Gyeong Jae Cho, Wan Sung Choi, and Hyun Joon Kim
    Experimental Neurobiology, 2019.04
  • Chronological aging standard curves of telomere length and mitochondrial DNA copy number in twelve tissues of C57BL/6 male mouse
    Ji Hyeong Baek, Hyeonwi Son, Young-Hoon Jeong, Sang Won Park, and Hyun Joon Kim
    Cells, 2019.03
  • Insufficient glutamine synthetase activity during synaptogenesis causes spatial memory impairment in adult mice
    Hyeonwi Son, Sujeong Kim, Doo-hyuk Jung, Ji Hyeong Baek, Dong Hoon Lee, Gu Seob Roh, Sang Soo Kang, Gyeong Jae Cho, Wan Sung Choi, Dong Kun Lee, and Hyun Joon Kim
    Scientific Reports, 2019.01.22
  • Glutamine has antidepressive effects through increments of glutamate and glutamine levels and glutamatergic activity in the medial prefrontal cortex
    Hyeonwi Son, Ji Hyeong Baek, Bok Soon Go, Doo-hyuk Jung, Sneha B. Sontakke, Hye Jin Chung, Dong Hoon Lee, Gu Seob Roh, Sang Soo Kang, Gyeong Jae Cho, Wan Sung Choi, Dong Kun Lee, Hyun Joon Kim
    Neuropharmacology, 2018.09
  • SDE5, a putative RNA export protein, participates in plant innate immunity through a flagellin-dependent signaling pathway in Arabidopsis
    Mohammad Nazim Uddin , Salina Akhter, Rupak Chakraborty, Ji Hyeong Baek, Joon-Yung Cha, Su Jung Park, Hunseung Kang, Woe-Yeon Kim, Sang Yeol Lee, David Mackey, Min Gab Kim
    Scientific Reports, 2017.08.29
  • Comparison and contrast of plant, yeast, and mammalian ER stress and UPR
    Rupak Chakraborty, Ji Hyeong Baek, Woe-Yeon Kim, Sang Yeol Lee, Min Gab Kim
    Applied Biological Chemistry, 2016.04
  • An Insulin-binding Protein from the Venom of a Solitary Wasp Binds to Apolipophorin III in Lepidopteran Hemolymph
    Ji Hyeong Baek,Si Hyeock Lee, Woe-Yeon Kim, Min Gab Kim
    Toxicon, 2016.03
  • Development of an antibody-based diagnostic method for the identification of Bemisia tabaci biotype B
    Ji Hyeong Baek, Hye Jung Lee, Young Ho Kim, Kook Jin Lim, Si Hyeock Lee, Bum Joon Kim
    Pesticide Biochemistry and Physiology, 2016.7
  • Differential properties of venom peptides and proteins in solitary vs. social hunting wasps
    Si Hyeock Lee, Ji Hyeong Baek, Kyungjae Andrew Yoon
    Toxins, 2016.1.22
  • N-Glycosylation process in both ER and Golgi plays pivotal role in plant immunity
    Byeong Sul Kang, Ji Hyeong Baek, Donah Mary Macoy, Rupak Chakraborty, Joon-Yung Cha, Duk-Ju Hwang, Yeon Hee Lee, Sang Yeol Lee, Woe-Yeon Kim, Min Gab Kim
    Journal of Plant Biology, 2015.12
  • Differential gene expression profiles in salivary gland of Orius laevigatus
    Ji Hyeong Baek and Si Hyeock Lee
    Journal of Asia-Pacific Entomology, 2014.12
  • Comparative transcriptome analysis of the venom sac and gland of a social wasp Vespa tropica and a solitary wasp Rhynchium brunneum
    Ji Hyeong Baek, Jung Hun Oh, Young Ho Kim, Si Hyeock Lee
    Journal of Asia-Pacific Entomology, 2013.12
  • Brief exposures of human body lice to sub-lethal amounts of ivermectin over transcribes detoxification genes involved in tolerance
    K. S. Yoon, J. P. Strycharz, Ji Hyeong Baek, W. Sun, Ju Hyun Kim, Jae Soon Kang, B.R. Pittendrigh, Si Hyeock Lee, John Marshall Clark
    Insect Molecular Biology, 2011.12.01
  • Venom peptides from solitary hunting wasps induce feeding disorder of lepidopteran larvae
    Ji Hyeong Baek, Jee, Yeounjung Ji, Jeon-Soo Shin, Seunghwan Lee, Si Hyeock Lee
    Peptides, 2011.03.01
  • Identification and characterization of venom proteins of two solitary wasps, Eumenes pomiformis and Orancistrocerus drewseni
    Ji Hyeong Baek, Si Hyeock Lee
    Toxicon, 2010.09.15
  • Differential gene expression profiles in the venom gland/sac of Eumenes pomiformis (Hymenoptera: Eumenidae)
    Ji Hyeong Baek, Si Hyeock Lee
    Toxicon, 2010.06.01
  • Isolation and molecular cloning of venom peptides from Orancistrocerus drewseni (Hymenoptera: Eumenidae)
    Ji Hyeong Baek, Si Hyeock Lee
    Toxicon, 2010.04.01
  • Cross-strain comparison of cypermethrin-induced cytochrome P450 transcription under different induction conditions in diamondback moth
    Ji Hyeong Baek, John Marshall Clark, Si Hyeock Lee
    Pesticide Biochemistry and Physiology, 2010.01
  • Differential gene expression profiles in the venom gland/sac of Orancistrocerus drewseni (Hymenoptera: Eumenidae)
    Ji Hyeong Baek, Tae Ha Woo, Chang Bae Kim, Jong Hwa Park, Hyojoong Kim, Seunghwan Lee, Si Hyeock Lee
    Archives of Insect Biochemistry and Physiology, 2009.08.01
  • Frequency detection of pyrethroid resistance allele in Anopheles sinensis populations by real-time PCR amplification of specific allele (rtPASA)
    Hyun Woo Ki, Ji Hyeong Baek, Won-Ja Lee, Si Hyeock Lee
    Pesticide Biochemistry and Physiology, 2007.01
  • Frequency detection of organophosphate Resistance allele in Anopheles sinensis (Diptera: Culicidae) populations by real-time PCR amplification of specific allele (rtPASA)
    Ji Hyeong Baek, Hyun Woo Kim, Won-Ja Lee, Si Hyeock Lee
    Journal of Asia-Pacific Entomology, 2006.12
  • Identification and characterization of ace1-type acetylcholinesterase likely associated with organophosphate resistance in Plutella xylostella
    Ji Hyeong Baek, Ju Il Kim, Dae-Weon Lee, Bu Keun Chung, Tadashi Miyata, Si Hyeock Lee
    Pesticide Biochemistry and Physiology, 2005.03